We are currently doing COVID-19 Antibody Testing, it is a four-antibody test that takes just three days to get results. This test is $200 and can be drawn in the clinic.
Below is information from our lab, Vibrant.
Vibrant Antibody Panel – 4 Viral Antigens and 3 Antibody classes – IgM, IgA, and IgG
While the value of antibody tests has been proven with a majority of testing available being able to detect antibodies to a single antigen such as nucleoprotein – the Vibrant Ab Panel is the only one to measure antibody levels against all 4 key antigens of the SARS-CoV-2 as listed below. It is also important to note we will report separately on 3 antibody subclasses – IgM, IgA and IgG– which can shed light on the broad immune response of the individual. Important highlights to note in our testing are below.
Testing for a single antigen will limit the assay sensitivity as we can see from the individual sensitivities and specificities of antigens listed in our validation document.
It is important to note that studies at Vibrant have been performed using swab positive and negative in the US population and do not rely on external studies.
The antigens were manufactured using the reference genome of SARS-CoV2 that was published and are hence specific to the novel coronavirus SARS-CoV2. Preliminary studies have shown differentiation from antibodies to other coronaviruses, however much larger studies are required to ascertain this which is why the FDA mandates a disclaimer in all antibody tests at this point on potential cross-reactivity.
Testing affected individuals at least twice may help display immune system modulation and also differentiate if the infection is recent vs past.
Vibrant uses chemiluminescence-based detection for all antibody subclasses in addition to a procedure called IgG stripping during the detection of IgM, which enhances the sensitivity of our assay.
Disclaimer for Covid-19 Antibody Testing
This test can detect the presence of COVID-19 antibodies for those who have developed an immune response to the virus. However, antibody testing should not be used as a sole basis to diagnose or exclude COVID-19 infection. Please note, this test has applied for FDA review under the Emergency Use Authorization Program (EUA) but is currently not FDA-approved.